Individual CardOut vs. 2 relationships for all subjects are shown in Fig. 2, top, with regression curves determined from overall mean values for regression coefficients in Fig. 2, bottom. Figure 3 shows mean regression curves from selected previous studies, largely using dye dilution techniques or direct Fick method to measure CardOut in both athletes and normal subjects. Our data lie in the low end of the range of most previous studies, although the present data closely match our own study using the direct Fick method to validate the open-circuit method used in this study.
Fig. 2.CardOut vs. 2. Each line represents 1 subject. Dashed and solid lines represent subjects with non-negative and significant negative quadratic term, respectively. Bottom: mean regression curves to compare groups. Open symbols, data from our previous validation study using direct Fick method; •, subjects with non-negative curvature term; ?, subjects with significant negative curvature.
Fig. 3.CardOut vs. 2 curves. Shown are mean regression curves to compare data from various sources. Open symbols, data from this study (circles) and our previous Fick validation study (squares); solid symbols, data from the literature.
Our subjects were analyzed in two groups: those with significant negative curvature of the CardOut vs. 2 curve and those whose curvature was either positive or not significantly negative. Figure 2, bottom, shows the mean regression curves for the two groups along with a mean regression for our Fick validation study. The average sum squared error of the model fit was significantly higher for the linear model compared with model with quadratic term in the negative curvature group, but not the nonnegative curvature group, confirming the model with curvature fit better in the negative curvature group sexfinder sign in. In the negative curvature group, 56% were male, whereas only 40% were male in the nonnegative curvature group, although this difference was not significant (P > 0.21, ? 2 test). The negative curvature group was slightly younger (median 26 vs. 30 yr; P = 0.049), tended to be heavier (median 81 vs. 69 kg; P = 0.06), but had similar body mass index values (median 24.9 vs. 23.5 kg/m 2 ; P = 0.16). The dos maximum/kg was higher (median 37.9 vs. 32.4 ml·min ?1 ·kg ?1 ; P = 0.03) in the negative curvature group, with a tendency for maximum CardOut to be higher (median 17.1 vs. 13.7 l/min, P = 0.06). The % predicted 2 max tended to be higher in the negative curvature group, but the difference was not significant (10). Resting HR was lower (median 72 vs. 82 beats/min; P = 0.04), and resting absolute SV higher (median 77 vs. 60 ml; P = 0.04) in the group with significant negative curvature. However, resting SV/BSA was similar in the two groups, as was maximal CardOut/BSA. Resting O2 extraction was similar, but maximal O2 extraction was higher (17.1 vs. 15.5 ml/100 ml; P < 0.01) in the negative curvature group. These data suggest a higher fitness level in the group with negative curvature.
Differences between this type of groups in both psychological variables and you may details derived from these contours get within the Dining tables 1 and you may 2
Values are means ± SD (with range in parentheses). Neg curve group, patients with a statistically significant negative CardOut vs. 2 curvature; Non-neg curve group, patients whose CardOut vs. 2 curvature was not statistically significantly negative; slope ratio, Winsorized ratio of final to initial slope of the CardOut vs. 2 curve (see text). Relative change is the relative change in the slope of the data between the last and second to last observation [(COn ? COn?step one)/COn?step one]. All P Values for comparison of group 1 and Group 2 are from Wilcoxon rank sum tests or ? 2 tests.
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